Macromolecular crowding: an important but neglected aspect of the intracellular environment.
Macromolecular crowding: an important but neglected aspect of the intracellular environment.
R. Ellis
2001 · DOI: 10.1016/S0959-440X(00)00172-X
Current Opinion in Structural Biology · 1,027 Citations
TLDR
It is proposed that the addition of crowding agents should become as routine as controlling pH and ionic strength if the authors are to meet the objective of studying biological molecules under more physiologically relevant conditions.