Lorcaserin and pimavanserin: emerging selectivity of serotonin receptor subtype-targeted drugs.
Lorcaserin and pimavanserin: emerging selectivity of serotonin receptor subtype-targeted drugs.
H. Meltzer,B. Roth
2013 · DOI: 10.1172/JCI70678
Journal of Clinical Investigation · 100 Citations
TLDR
Two recent 5-HT receptor subtype-selective drugs, lorcaserin and pimavanserin, are discussed, which target the 5HT2C and5HT2A receptors and provide new treatments for obesity and Parkinson's disease psychosis, respectively.