Lipase inhibitor orlistat prevents hepatitis B virus infection by targeting an early step in the virus life cycle.
Lipase inhibitor orlistat prevents hepatitis B virus infection by targeting an early step in the virus life cycle.
Knud Esser,J. Lucifora,4 Authors,U. Protzer
2018 · DOI: 10.1016/j.antiviral.2018.01.001
Antiviral Research · 14 Citations
TLDR
The data indicate that HBV connects to the hepatotropic lipoprotein metabolism and that inhibition of cellular hepatic lipase(s) may allow to target early steps of HBV infection.