let-7 microRNAs in development, stem cells and cancer.
let-7 microRNAs in development, stem cells and cancer.
I. Büssing,F. Slack,H. Grosshans
2008 · DOI: 10.1016/j.molmed.2008.07.001
Trends in Molecular Medicine · 610 Citations
TLDR
It is proposed that let-7 regulates 'stemness' by repressing self-renewal and promoting differentiation in both normal development and cancer.