Ketamine and MAG Lipase Inhibitor-Dependent Reversal of Evolving Depressive-Like Behavior During Forced Abstinence From Alcohol Drinking
Ketamine and MAG Lipase Inhibitor-Dependent Reversal of Evolving Depressive-Like Behavior During Forced Abstinence From Alcohol Drinking
K. Holleran,H. H. Wilson,6 Authors,D. Winder
2016 · DOI: 10.1038/npp.2016.3
Neuropsychopharmacology · 84 Citations
TLDR
It is demonstrated that the depressive behaviors observed do not require a sucrose fade and that this drinking paradigm may favor the development of habit-like EtOH consumption, which could set the stage for developing novel treatment approaches for alcohol-withdrawal-induced mood and anxiety disorders.