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Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom

Neva C. Durand,James T. Robinson,4 Authors,Erez Lieberman Aiden

2016 · DOI: 10.1016/j.cels.2015.07.012
Cell Systems · 2,186 Citations

TLDR

Juicebox is introduced, a tool for exploring Hi-C and other contact map data that allows users to zoom in and out of Hi-C maps interactively, just as a user of Google Earth might zoom in and out of a geographic map.

Abstract

Hi-C experiments study how genomes fold in 3D, generating contact maps containing features as small as 20bp and as large as 200-Mb. Here we introduce Juicebox, a tool for exploring Hi-C and other contact map data. Juicebox allows users to zoom in and out of Hi-C maps interactively, just as a user of Google Earth might zoom in and out of a geographic map. Maps can be compared to one another, or to 1D tracks or 2D feature sets.