Intracavernosal vascular endothelial growth factor (VEGF) injection and adeno-associated virus-mediated VEGF gene therapy prevent and reverse venogenic erectile dysfunction in rats
Intracavernosal vascular endothelial growth factor (VEGF) injection and adeno-associated virus-mediated VEGF gene therapy prevent and reverse venogenic erectile dysfunction in rats
Rodman S. Rogers,Tulio M. Graziottin,2 Authors,T. Lue
2003 · DOI: 10.1038/sj.ijir.3900943
International journal of impotence research · 188 Citations
TLDR
Investigation of whether vascular endothelial growth factor (VEGF) can be used to prevent and reverse venogenic ED in a rat model found systemic testosterone replacement or intracavernous V EGF (protein and VEGF gene) prevented the veno-occlusive dysfunction in castrated animals.