Inflammatory tumor microenvironment responsive neutrophil exosomes-based drug delivery system for targeted glioma therapy.
Inflammatory tumor microenvironment responsive neutrophil exosomes-based drug delivery system for targeted glioma therapy.
Jun Wang,Wei Tang,7 Authors,Yazhou Wang
2021 · DOI: 10.1016/j.biomaterials.2021.120784
Biomaterials · 224 Citations
TLDR
NEs-Exos is confirmed to have neutrophil-like chemotactic function and BBB penetration and represents a promising chemotherapeutic approach for clinical treatment of glioma and other solid tumor or brain diseases.
