In vivo multimodality imaging and cancer therapy by near-infrared light-triggered trans-platinum pro-drug-conjugated upconverison nanoparticles.
In vivo multimodality imaging and cancer therapy by near-infrared light-triggered trans-platinum pro-drug-conjugated upconverison nanoparticles.
Yunlu Dai,Haihua Xiao,8 Authors,Jun Lin
2013 · DOI: 10.1021/ja410028q
Journal of the American Chemical Society · 491 Citations
TLDR
A multifunctional drug delivery system combining upconversion luminescence/magnetic resonance/computer tomography trimodality imaging and NIR-activated platinum pro-drug delivery by converting NIR light into UV for control of drug activity in practical cancer therapy is developed.