In vivo determination of muscarinic acetylcholine receptor availability in schizophrenia.
In vivo determination of muscarinic acetylcholine receptor availability in schizophrenia.
T. Raedler,M. Knable,6 Authors,D. Weinberger
2003 · DOI: 10.1176/APPI.AJP.160.1.118
American Journal of Psychiatry · 218 Citations
TLDR
Results indicate a reduction in muscarinic acetylcholine receptor availability in vivo in unmedicated patients with schizophrenia, confirming results from postmortem studies and adding further evidence that the muscaric system is involved in the pathophysiology of schizophrenia.