In vitro osteogenesis of human adipose-derived stem cells by coculture with human umbilical vein endothelial cells.
In vitro osteogenesis of human adipose-derived stem cells by coculture with human umbilical vein endothelial cells.
Jian Wang,Yaping Ye,4 Authors,Yukun Zhang
2011 · DOI: 10.1016/j.bbrc.2011.07.062
Biochemical and Biophysical Research Communications - BBRC · 41 Citations
TLDR
In vitro osteogenesis of hASCs was enhanced by coculture with HUVEC which secreted BMP-2 and this provided an in vitro model of studying interaction between cells, but also helped to understand the in vivo therapeutic mechanisms of ASCs.