In situ protection methodology in carbonyl chemistry.
In situ protection methodology in carbonyl chemistry.
Kenzo Yahata,H. Fujioka
2014 · DOI: 10.1248/CPB.C13-00732
Chemical and pharmaceutical bulletin · 17 Citations
TLDR
This review discusses various in situ protection strategies and their synthetic applications and describes recent progress in selective transformation of carbonyl groups using in situprotection methodology.
Abstract
Recent progress in selective transformation of carbonyl groups using in situ protection methodology is described. These techniques which enable reversing reactivity of functional groups have potential usefulness because they can remove complicated protection-deprotection sequences. In this review, we discuss various in situ protection strategies and their synthetic applications.