Impact of antibiotic-resistant bacteria in the mouse intestine on immune activation and Clostridioides difficile infection.
Impact of antibiotic-resistant bacteria in the mouse intestine on immune activation and Clostridioides difficile infection.
J. Keith,Qiwen Dong,7 Authors,E. Pamer
2020 · DOI: 10.1128/IAI.00362-19
Infection and Immunity · 7 Citations
TLDR
The results suggest that the virulence mechanisms enabling C. difficile infection (CDI) and epithelial destruction outweigh the relatively minor impact of less virulent, antibiotic-resistant intestinal bacteria on the outcome of CDI.