Hyperferritinemia as indicator for intravenous immunoglobulin treatment in reactive macrophage activation syndromes
Hyperferritinemia as indicator for intravenous immunoglobulin treatment in reactive macrophage activation syndromes
U. Emmenegger,U. Frey,5 Authors,K. Neftel
2001 · DOI: 10.1002/AJH.1141
American journal of hematology/oncology · 146 Citations
TLDR
In conclusion, IVIG is effective in at least a subgroup of adult rMAS when started at the beginning of the macrophage activation process, and the monitoring of serum ferritin levels might be helpful in detecting macrophages activation in order to commence IVIG treatment early enough.