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Human postmortem tissue: what quality markers matter?

A. Stan,S. Ghose,4 Authors,C. Tamminga

2006 · DOI: 10.1016/J.BRAINRES.2006.09.025
Brain Research · 362 Citations

TLDR

This work measured tissue quality parameters in over 100 postmortem cases collected from different sources and correlated them with RNA quality (as indicated by the RNA Integrity Number (RIN) and with protein quality ( as measured by the level of representative proteins), showing that the most sensible indicator of tissue quality is RIN and that there is a good correlation between RIN