How colonization by microbiota in early life shapes the immune system
How colonization by microbiota in early life shapes the immune system
Thomas Gensollen,S. Iyer,Dennis L. Kasper,R. Blumberg
2016 · DOI: 10.1126/science.aad9378
Science · 1,684 Citations
TLDR
The role of early-life education of the immune system during this “window of opportunity,” when disruption of optimal host-commensal interactions can lead to persistent and in some cases irreversible defects in the development and training of specific immune subsets is discussed.