High-Throughput Plasmodium falciparum Growth Assay for Malaria Drug Discovery
High-Throughput Plasmodium falciparum Growth Assay for Malaria Drug Discovery
M. Baniecki,D. Wirth,J. Clardy
2006 · DOI: 10.1128/AAC.01144-06
Antimicrobial Agents and Chemotherapy · 178 Citations
TLDR
A P. falciparum growth assay is reported that is technically simple, robust, and compatible with the automation necessary for HTS, and 181 small molecules were identified as highly active against multidrug-resistant parasites.