HHblits: lightning-fast iterative protein sequence searching by HMM-HMM alignment
HHblits: lightning-fast iterative protein sequence searching by HMM-HMM alignment
M. Remmert,Andreas Biegert,A. Hauser,J. Söding
2011 · DOI: 10.1038/nmeth.1818
Nature Methods · 2,251 Citations
TLDR
An open-source, general-purpose tool that represents both query and database sequences by profile hidden Markov models (HMMs): 'HMM-HMM–based lightning-fast iterative sequence search' (HHblits; http://toolkit.genzentrum.lmu.de/hhblits/).