Hepatocyte deformation induced by cyanobacterial toxins reflects inhibition of protein phosphatases.
Hepatocyte deformation induced by cyanobacterial toxins reflects inhibition of protein phosphatases.
John E. Eriksson,Diana M. Toivola,3 Authors,D. Hartshorne
1990 · DOI: 10.1016/S0006-291X(05)80936-2
Biochemical and Biophysical Research Communications - BBRC · 337 Citations
TLDR
Evidence is presented to indicate that in hepatocytes the morphological changes and effects on the cytoskeleton are due to phosphatase inhibition, and the importance of the protein phosphorylation in maintenance of structural and homeostatic integrity in these cells is indicated.