Genome-wide linkage analysis of quantitative biomarker traits of osteoarthritis in a large, multigenerational extended family.
Genome-wide linkage analysis of quantitative biomarker traits of osteoarthritis in a large, multigenerational extended family.
Hsian-Cheng Chen,V. Kraus,8 Authors,Svati H. Shah
2010 · DOI: 10.1002/art.27288
Arthritis & Rheumatism · 20 Citations
TLDR
The results demonstrate that serum concentrations of PIIANP, HA, COMP, and C2C have substantial heritable components, and using these biomarkers, several genetic loci potentially contributing to the genetic diversity of OA were identified.