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Genetics and pathogenesis of inflammatory bowel disease

B. Khor,A. Gardet,R. Xavier

2011 · DOI: 10.1038/nature10209
Nature · 1,563 Citations

TLDR

Recent advances have provided substantial insight into the maintenance of mucosal immunity and the pathogenesis of inflammatory bowel disease, and the role of genetic predispositions and how they affect interactions with microbial and environmental factors is emphasized.