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General Anesthesia, Sleep, and Coma

E. Brown,R. Lydic,N. Schiff

2010 · DOI: 10.1056/NEJMra0808281
New England Journal of Medicine · 1,214 Citations

TLDR

This review discusses the clinical and neurophysiological features of general anesthesia and their relationships to sleep and coma, focusing on the neural mechanisms of unconsciousness induced by selected intravenous anesthetic drugs.

Abstract

This review discusses the clinical and neurophysiological features of general anesthesia and their relationships to sleep and coma, focusing on the neural mechanisms of unconsciousness induced by selected intravenous anesthetic drugs.