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From big data and experimental models to clinical trials: Iterative strategies in microbiome research

S. Turjeman,Tommaso Rozera,2 Authors,Omry Koren

2025 · DOI: 10.1016/j.cell.2025.01.038
Cell · 12 Citations

TLDR

The persistence of correlational studies in microbiome research is discussed and an iterative method leveraging in silico, in vitro, ex vivo, and in vivo studies toward successful preclinical and clinical trials is proposed, highlighting the importance of combining traditional microbiological techniques with big-data approaches.