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Fast and sensitive protein alignment using DIAMOND

Benjamin Buchfink,C. Xie,D. Huson

2014 · DOI: 10.1038/nmeth.3176
Nature Methods · 11,594 Citations

TLDR

DIAMOND is introduced, an open-source algorithm based on double indexing that is 20,000 times faster than BLASTX on short reads and has a similar degree of sensitivity.