Fabrication of gradient hydrogels using a microfluidics/photopolymerization process.
Fabrication of gradient hydrogels using a microfluidics/photopolymerization process.
J. Burdick,A. Khademhosseini,R. Langer
2004 · DOI: 10.1021/LA049298N
Langmuir · 362 Citations
TLDR
The technique is investigated both through fabrication of adhesive ligand gradients that modulate spatial distribution of attached endothelial cells and gradients of cross-linking densities that led to unique hydrogel architectures and spatially dependent swelling.
