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Fabrication of gradient hydrogels using a microfluidics/photopolymerization process.

J. Burdick,A. Khademhosseini,R. Langer

2004 · DOI: 10.1021/LA049298N
Langmuir · 362 Citations

TLDR

The technique is investigated both through fabrication of adhesive ligand gradients that modulate spatial distribution of attached endothelial cells and gradients of cross-linking densities that led to unique hydrogel architectures and spatially dependent swelling.