Exploring the immunomodulatory effects of turmeric on antibody responses in vaccinated broilers against Newcastle and Gumboro diseases

ABSTRACT This study investigates the immunomodulatory effects of turmeric (Curcuma longa) supplementation on antibody production in vaccinated chicks against Newcastle Disease (ND) and Gumboro Disease (IBD). A total of 490 experimental chicks were divided into five groups, each receiving varying doses of turmeric (1g, 2.5g, 5g, and 10g) alongside vaccination, with a control group receiving no turmeric. Serum antibody levels were assessed using the ELISA test at 14- and 21-days post-vaccination. Results indicated a significant increase in antibody titers in the turmeric-supplemented groups compared to the control group, demonstrating a dose-dependent response, with the highest titers observed at 10g of turmeric. At 21 days, the antibody levels for Newcastle Disease reached 5585 standard units in the group receiving 10g of turmeric, contrasting with 3993 standard units in the control group. For Gumboro Disease, the highest antibody levels were noted in the group receiving 10g of turmeric, significantly surpassing the control group. These findings suggest that turmeric supplementation effectively enhances the immune response to vaccinations in poultry, providing a natural alternative for improving disease resistance and overall health in broiler chickens. The study highlights the potential for integrating turmeric into poultry management practices to support vaccine efficacy and improve production outcomes.