Estrogens stimulate serotonin neurons to inhibit binge-like eating in mice.
Estrogens stimulate serotonin neurons to inhibit binge-like eating in mice.
Xuehong Cao,Pingwen Xu,19 Authors,Yong Xu
2014 · DOI: 10.1172/JCI74726
Journal of Clinical Investigation · 105 Citations
TLDR
It is shown that estrogen replacement substantially suppresses binge-like eating behavior in ovariectomized female mice and suggests ERα and/or SK current in DRN 5-HT neurons as potential targets for anti-binge therapies.