Estrogenic activity of octylphenol, nonylphenol, bisphenol A and methoxychlor in rats.

In vivo studies indicated that the 3-day uterotrophic assay in prepubertal rats was the best method for detecting estrogenic activity when compared with all other end points, based upon the dose-response data for ethynyl estradiol and 4-tert-octylphenol.