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Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.

W. T. Friedewald,R. Levy,D. Fredrickson

1972 · DOI: 10.1093/CLINCHEM/18.6.499
Clinical Chemistry · 33,090 Citations

TLDR

A method for estimating the cholesterol content of the serum low-density lipoprotein fraction (Sf0-20) is presented and comparison of this suggested procedure with the more direct procedure, in which the ultracentrifuge is used, yielded correlation coefficients of .94 to .99.

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