Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells
Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells
A. Aicher,C. Heeschen,5 Authors,S. Dimmeler
2003 · DOI: 10.1038/nm948
Nature Medicine · 1,423 Citations
TLDR
It is indicated that eNOS expressed by bone marrow stromal cells influences recruitment of stem and progenitor cells, which may contribute to impaired regeneration processes in ischemic heart disease patients, who are characterized by a reduced systemic NO bioactivity.