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Enhancing Effect of Hydroxyurea on Hb F in Sickle Cell Disease: Ten-Year Egyptian Experience

Ilham Youssry,A. Abdel-Salam,4 Authors,A. Taher

2017 · DOI: 10.1080/03630269.2017.1408646
Hemoglobin · 6 Citations

TLDR

Hydroxyurea induced an increase in Hb F level, which was maintained over time and was associated with clinical efficacy and acceptable safety, and a significant reduction in the frequency of VOCs, transfusion frequency and hospital admissions per year after HU therapy was shown in the studied subjects.