Enhanced expression of TGF-betas and their receptors in human acute pancreatitis.
Enhanced expression of TGF-betas and their receptors in human acute pancreatitis.
H. Friess,Z. Lu,6 Authors,M. Büchler
1998 · DOI: 10.1097/00000658-199801000-00014
Annals of Surgery · 85 Citations
TLDR
A marked increase in expression of TGF-betas and their signaling receptors T beta-RI (ALK5) and Tbeta-RII suggests a role for TGF"-betas in the repair process after the onset of NP in humans and raises the possibility that TGF -betas might be involved in tissue remodeling and the fibrotic reaction that occurs in the pancreas after necrosis.