Emerging Principles for the Therapeutic Exploitation of Glycosylation
Emerging Principles for the Therapeutic Exploitation of Glycosylation
M. Dalziel,M. Crispin,2 Authors,R. Dwek
2014 · DOI: 10.1126/science.1235681
Science · 420 Citations
TLDR
The current knowledge of glycans in pathogen invasion, cancer, autoimmunity, and congenital diseases is reviewed and glycan engineering will continue to deliver enhanced therapeutic glycoproteins, such as antibodies, with enhanced disease modifying properties.
