Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion.
Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion.
T. Yeung,Penelope C. Georges,7 Authors,P. Janmey
2005 · DOI: 10.1002/CM.20041
Cell Motility and the Cytoskeleton · 2,396 Citations
TLDR
The hypothesis that mechanical factors impact different cell types in fundamentally different ways, and can trigger specific changes similar to those stimulated by soluble ligands, is supported.