Effects of Phytoestrogen Extracts Isolated from Pumpkin Seeds on Estradiol Production and ER/PR Expression in Breast Cancer and Trophoblast Tumor Cells
Effects of Phytoestrogen Extracts Isolated from Pumpkin Seeds on Estradiol Production and ER/PR Expression in Breast Cancer and Trophoblast Tumor Cells
D. Richter,S. Abarzua,11 Authors,D. Dian
2013 · DOI: 10.1080/01635581.2013.797000
Nutrition and Cancer · 31 Citations
TLDR
Estradiol production was elevated in MCF7, BeWo, and Jeg3 cells in a concentration-dependent manner and asignificant ER-α downregulation and a significant PR upregulation were observed.