Effect of stiffness of chitosan-hyaluronic acid dialdehyde hydrogels on the viability and growth of encapsulated chondrocytes.
Effect of stiffness of chitosan-hyaluronic acid dialdehyde hydrogels on the viability and growth of encapsulated chondrocytes.
Lynda V. Thomas,Rahul Vg,Prabha D Nair
2017 · DOI: 10.1016/j.ijbiomac.2017.05.116
International Journal of Biological Macromolecules · 58 Citations
TLDR
Findings indicate that gel stiffness strongly impacts the chondrocyte microenvironment both in maintenance of phenotypic integrity and ECM production.