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Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial.

J. Johnstone,M. Meade,497 Authors,Louis-Étienne Marchand

2021 · DOI: 10.1001/jama.2021.13355
Journal of the American Medical Association (JAMA) · 167 Citations

TLDR

Among critically ill patients requiring mechanical ventilation, administration of the probiotic L rhamnosus GG compared with placebo resulted in no significant difference in the development of ventilator-associated pneumonia, and these findings do not support the use of L rhenobacillus GG in critical ill patients.