Effect of chitosan coating in overcoming the phagocytosis of insulin loaded solid lipid nanoparticles by mononuclear phagocyte system
Effect of chitosan coating in overcoming the phagocytosis of insulin loaded solid lipid nanoparticles by mononuclear phagocyte system
B. Sarmento,Donatella Mazzaglia,3 Authors,V. Seabra
2011 · DOI: 10.1016/J.CARBPOL.2010.12.042
98 Citations
TLDR
Chitosan-coated SLN demonstrated to be potentially able to prolong insulin blood levels and to avoid phagocytosis by MPS after intestinal uptake and quantitatively confirmed by flow cytometry assay.