DNA/Lipid complex incorporated with fibronectin to cell adhesion enhances transfection efficiency in prostate cancer cells and xenografts.
DNA/Lipid complex incorporated with fibronectin to cell adhesion enhances transfection efficiency in prostate cancer cells and xenografts.
Y. Hattori,Y. Maitani
2007 · DOI: 10.1248/BPB.30.603
Biological and Pharmaceutical Bulletin · 13 Citations
TLDR
Among the ECM proteins, Fn-coating nanoplexes significantly increased transfection activity 2-fold in prostate cancer PC-3 cells, and exhibited higher DNA transfections activities to PC- 3 xenografts, compared with commercially available cationic polymer in vivo jetPEI.