Direct observation of a condensate effect on super-enhancer controlled gene bursting
Manyu Du,Simon H. Stitzinger,5 Authors,I. Cissé
2023 · DOI: 10.1016/j.cell.2023.12.005
Cell · 83 Citations
TLDR
This work develops live-cell super-resolution and multi-color 3D-imaging approaches and proposes a three-way kissing model whereby the condensate interacts transiently with gene locus and regulatory DNA elements to control gene bursting.
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