Differences in cumulus cell gene expression indicate the benefit of a pre-maturation step to improve in-vitro bovine embryo production.
Differences in cumulus cell gene expression indicate the benefit of a pre-maturation step to improve in-vitro bovine embryo production.
C. Dieci,V. Lodde,4 Authors,A. M. Luciano
2016 · DOI: 10.1093/MOLEHR/GAW055
Molecular human reproduction · 51 Citations
TLDR
Based on the analysis of CC transcriptomic profiles and the relationship between morphological features of the COC and the oocyte chromatin configuration, a customized, stage-dependent oocyte pre-maturation (pre-IVM) system was used to improve oocyte developmental potential before IVM.