Development of autoantibodies before the clinical onset of systemic lupus erythematosus.
Development of autoantibodies before the clinical onset of systemic lupus erythematosus.
M. Arbuckle,M. McClain,4 Authors,J. Harley
2003 · DOI: 10.1056/NEJMOA021933
New England Journal of Medicine · 2,477 Citations
TLDR
The onset and progression of autoantibody development before the clinical diagnosis of systemic lupus erythematosus is investigated, with a progressive accumulation of specificAutoantibodies before the onset of SLE, while patients are still asymptomatic.