Design considerations for effective neural signal sensing and amplification: a review

An electronic system comprising of significant circuit blocks like sensors (to capture the right strength of signals) and Low Noise Amplifier (to suitably amplify the same) are required for proper diagnosis of any brain-related chronic diseases or temporary neurological disorders. Challenges regarding the design of a complete neural system have been understood by researchers in bits and pieces without actually somebody threading this important piece of information for use in future by research community in this field. We in this paper, provide an overview of neural signal modalities, summary of different neural signal sensing elements, specifications in designing an ideal neural amplifier, discussions pertaining to tradeoffs and inter-dependency between different parameters of neural amplifiers. Paper also presents a detailed piece of information about the state-of-the-art of these design parameters while comparing the results obtained by various researchers with the help of graphs, tables, and suitable figures. A comprehensive information presented in this way would help the reader to appreciate the intricacies of this much challenging field in an even detailed manner with the most appropriate reference citation for the same.