Derivation and Validation of a Mathematical Model for Predicting the Response to Exogenous Recombinant Human Growth Hormone (GH) in Prepubertal Children with Idiopathic GH Deficiency
Derivation and Validation of a Mathematical Model for Predicting the Response to Exogenous Recombinant Human Growth Hormone (GH) in Prepubertal Children with Idiopathic GH Deficiency
M. Ranke,A. Lindberg,4 Authors,D. Price
1999 · DOI: 10.1210/JCEM.84.4.5634
269 Citations
TLDR
The aim was to produce models that would have practical utility for predicting prepubertal growth during each of the first 4 yr of GH replacement therapy, and these models were validated by a prospective comparison of predicted and observed growth outcomes in an additional 3 cohorts of p...