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Delineation of prognostic biomarkers in prostate cancer

S. Dhanasekaran,T. Barrette,6 Authors,A. Chinnaiyan

2001 · DOI: 10.1038/35090585
Nature · 1,749 Citations

TLDR

Two genes—hepsin, a transmembrane serine protease, and pim-1, a serine/threonine kinase—are assessed at the protein level using tissue microarrays consisting of over 700 clinically stratified prostate-cancer specimens and linked clinical and pathology data are established.