Defensive Mutualism Rescues NADPH Oxidase Inactivation in Gut Infection.
Defensive Mutualism Rescues NADPH Oxidase Inactivation in Gut Infection.
G. Pîrcălăbioru,G. Aviello,7 Authors,U. Knaus
2016 · DOI: 10.1016/j.chom.2016.04.007
Cell Host and Microbe · 87 Citations
TLDR
It was discovered that NOX1 regulates DUOX2 expression in the intestinal epithelium, which magnified the epithelial ROS-deficiency, and epithelial deficiency of Cyba resulted in protection from C. rodentium and L. monocytogenes infection.