Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation
Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation
Stéphane Mouret,C. Baudouin,3 Authors,T. Douki
2006 · DOI: 10.1073/pnas.0604213103
Proceedings of the National Academy of Sciences of the United States of America · 637 Citations
TLDR
It is shown that human skin efficiently protects against UVB-induced DNA lesions, whereas very weak protection is afforded against UVA, which emphasize the likely role played by the UVA- induced DNA damage in skin carcinogenesis and should have consequences for photoprotection strategies.