Curcumin-laden exosomes target ischemic brain tissue and alleviate cerebral ischemia-reperfusion injury by inhibiting ROS-mediated mitochondrial apoptosis.
Curcumin-laden exosomes target ischemic brain tissue and alleviate cerebral ischemia-reperfusion injury by inhibiting ROS-mediated mitochondrial apoptosis.
Ruyi He,Yibing Jiang,2 Authors,Liang Zhao
2020 · DOI: 10.1016/j.msec.2020.111314
Materials Science and Engineering C: Materials for Biological Applications · 118 Citations
TLDR
Good therapeutic efficacy of Ex-cur is demonstrated for treating I/R injury, providing experimental evidence for the potential clinical benefits of exosomes loaded with curcumin for other modes of neuroprotection.