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Crystallization and preliminary X-ray crystallographic analysis of peptide deformylase (PDF) from Bacillus cereus in ligand-free and actinonin-bound forms.

Joon Kyu Park,J. Moon,Jae-Hong Kim,E. Kim

2005 · DOI: 10.1107/S1744309104032440
Acta Crystallographica. Section F : Structural Biology and Crystallization Communications · 8 Citations

TLDR

In bacteria, protein expression initiates with an N-formyl group and this needs to be removed in order to ensure proper bacterial growth and inhibition of these processes would provide a novel antibacterial therapy.