Crystallization and preliminary X-ray crystallographic analysis of peptide deformylase (PDF) from Bacillus cereus in ligand-free and actinonin-bound forms.
Crystallization and preliminary X-ray crystallographic analysis of peptide deformylase (PDF) from Bacillus cereus in ligand-free and actinonin-bound forms.
Joon Kyu Park,J. Moon,Jae-Hong Kim,E. Kim
2005 · DOI: 10.1107/S1744309104032440
Acta Crystallographica. Section F : Structural Biology and Crystallization Communications · 8 Citations
TLDR
In bacteria, protein expression initiates with an N-formyl group and this needs to be removed in order to ensure proper bacterial growth and inhibition of these processes would provide a novel antibacterial therapy.
