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County-Level Atrazine Use and Gastroschisis

Sunaya Krishnapura,Elizabeth McNeer,William D. Dupont,Stephen W. Patrick

2024 · DOI: 10.1001/jamanetworkopen.2024.10056
JAMA Network Open · 9 Citations

TLDR

Findings suggest that exploring alternatives to atrazine in the US may be warranted and higher levels of atrazine use at the county level were associated with an increased incidence of gastroschisis.

Abstract

Key Points Question What is the association of county-level atrazine use with infant diagnoses of gastroschisis? Findings In this cross-sectional study of nearly 40 million US births between 2009 and 2019, White race, young age, lower body mass index and parity, cigarette smoking, rurality, and Chlamydia infection during pregnancy were associated with gastroschisis. Additionally, higher levels of atrazine use at the county level were associated with an increased incidence of gastroschisis. Meaning These findings suggest that exploring alternatives to atrazine in the US may be warranted.